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Epitalon
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Detailed information
1. Basic Information
Product Name: Epitalon
English name: Epitalon
Amino acid sequence: Ala-Glu-Asp-Gly
Molecular formula: C 14 H 22 N 4 O 9
Molecular weight: 390.35
CAS Number: 307297-39-8
Structural diagram:
2. Feature Introduction
Mechanism of action
Telomerase activation: By activating telomerase, telomere length is extended, thereby delaying cellular senescence (supported by in vitro experiments); and regulating the expression of genes associated with aging (such as p53 and SIRT1).
Antioxidant and DNA Repair: Reduces the accumulation of reactive oxygen species (ROS) and enhances DNA damage repair capacity; upregulates antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase.
Pineal gland function regulation: regulates melatonin secretion and improves circadian rhythm disturbances; may influence the body’s overall aging process via the hypothalamic-pituitary axis.
Physiological and pharmacological effects
Anti-aging and lifespan extension: Animal studies (in mice and fruit flies) have shown that lifespan can be extended by approximately 10–30%, and age-related phenotypes—such as graying fur and reduced mobility—are diminished. Additionally, stem cell aging is delayed, helping to maintain tissue regenerative capacity.
Immune modulation: Enhances immune function in elderly individuals and restores thymic activity.
Neuroprotection: Improves cognitive function in Alzheimer’s disease models and reduces β-amyloid plaque deposition.
Anti-cancer potential: By regulating telomeres, it inhibits the unlimited proliferation of certain cancer cells.
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